Cargando…

SH3BP2 Gain-Of-Function Mutation Exacerbates Inflammation and Bone Loss in a Murine Collagen-Induced Arthritis Model

OBJECTIVE: SH3BP2 is a signaling adapter protein which regulates immune and skeletal systems. Gain-of-function mutations in SH3BP2 cause cherubism, characterized by jawbone destruction. This study was aimed to examine the role of SH3BP2 in inflammatory bone loss using a collagen-induced arthritis (C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mukai, Tomoyuki, Gallant, Richard, Ishida, Shu, Yoshitaka, Teruhito, Kittaka, Mizuho, Nishida, Keiichiro, Fox, David A., Morita, Yoshitaka, Ueki, Yasuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140794/ https://www.ncbi.nlm.nih.gov/pubmed/25144740 http://dx.doi.org/10.1371/journal.pone.0105518

Ejemplares similares

RANKL-independent osteoclastogenesis in the SH3BP2 cherubism mice
por: Kittaka, Mizuho, et al.
Publicado: (2020)

Sh3bp2 Gain-Of-Function Mutation Ameliorates Lupus Phenotypes in B6.MRL-Fas(lpr) Mice
por: Nagasu, Akiko, et al.
Publicado: (2019)

SH3BP2 Deficiency Ameliorates Murine Systemic Lupus Erythematosus
por: Kawahara, Kyoko, et al.
Publicado: (2021)

Tankyrase (PARP5) Inhibition Induces Bone Loss through Accumulation of Its Substrate SH3BP2
por: Mukai, Tomoyuki, et al.
Publicado: (2019)

Microbe‐Dependent Exacerbated Alveolar Bone Destruction in Heterozygous Cherubism Mice
por: Kittaka, Mizuho, et al.
Publicado: (2020)

OC_Finder: Osteoclast Segmentation, Counting, and Classification Using Watershed and Deep Learning
por: Wang, Xiao, et al.
Publicado: (2022)

Dagger Sign in Ankylosing Spondylitis
por: Mukai, Tomoyuki, et al.
Publicado: (2021)

Deletion of Mir223 Exacerbates Lupus Nephritis by Targeting S1pr1 in Fas(lpr/lpr) Mice
por: Hiramatsu-Asano, Sumie, et al.
Publicado: (2021)

Tlr2/4‐Mediated Hyperinflammation Promotes Cherubism‐Like Jawbone Expansion in Sh3bp2 (P416R) Knockin Mice
por: Fujii, Yasuyuki, et al.
Publicado: (2021)

Obesity and Dyslipidemia Synergistically Exacerbate Psoriatic Skin Inflammation
por: Ikeda, Kenta, et al.
Publicado: (2022)

Editorial: A new frontier in translational research on autoinflammatory diseases - various aspects of innate immunity on human diseases
por: Mukai, Tomoyuki, et al.
Publicado: (2023)

Barium‐induced pneumatosis intestinalis in a patient with anti‐synthetase syndrome
por: Yamamoto, Shintaro, et al.
Publicado: (2021)

Bacteremia Possibly Caused by Helicobacter cinaedi and Associated with Painful Erythema in Rheumatoid Arthritis with Malignant Lymphoma
por: Fujita, Shunichi, et al.
Publicado: (2018)

Infection of Helicobacter cinaedi Should Be Treated for an Adequate Duration with Combined Antibiotic Therapy: Author's Reply
por: Fujita, Shunichi, et al.
Publicado: (2019)

Paraneoplastic Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome Should Be Treated with Low-dose Prednisolone During Pembrolizumab Therapy
por: Yamamoto, Shintaro, et al.
Publicado: (2019)

The role of SH3BP2 in the pathophysiology of cherubism
por: Reichenberger, Ernst J, et al.
Publicado: (2012)

Osteocytes directly regulate osteolysis via MYD88 signaling in bacterial bone infection
por: Yoshimoto, Tetsuya, et al.
Publicado: (2022)

BP180/Collagen XVII: A Molecular View
por: Tuusa, Jussi, et al.
Publicado: (2021)

Structural basis of guanine nucleotide exchange for Rab11 by SH3BP5
por: Goto-Ito, Sakurako, et al.
Publicado: (2019)

Short-term outcomes of mirogabalin in patients with peripheral neuropathic pain: a retrospective study
por: Tetsunaga, Tomoko, et al.
Publicado: (2020)

Suppressive effects of the neutrophil elastase inhibitor sivelestat sodium hydrate on interleukin-1β production in lipopolysaccharide-stimulated porcine whole blood
por: Kurimoto, Yasuyoshi, et al.
Publicado: (2020)

Acute exacerbation of interstitial pneumonia associated with collagen vascular diseases
por: Suda, Takafumi, et al.
Publicado: (2009)

Effect of Angiotensin II on Bone Erosion and Systemic Bone Loss in Mice with Tumor Necrosis Factor-Mediated Arthritis
por: Akagi, Takahiko, et al.
Publicado: (2020)

A novel mutation in the SH3BP2 gene causes cherubism: case report
por: Li, Cui-Ying, et al.
Publicado: (2006)

The “Ant-farm”-like Appearance of Restricted Lower Limb Vasculitis on Fluorodeoxyglucose-positron Emission Tomography
por: Yamamoto, Shintaro, et al.
Publicado: (2021)

Effect of Tramadol/Acetaminophen on Motivation in Patients with Chronic Low Back Pain
por: Tetsunaga, Tomoko, et al.
Publicado: (2016)

Acetaminophen Exacerbates Hypertension: A #NephJC Editorial on PATH-BP
por: John, Priyadarshini, et al.
Publicado: (2022)

The dysfunction of BP180/collagen XVII in keratinocytes promotes melanoma progression.
por: Hwang, Bin-Jin, et al.
Publicado: (2019)

Breathing–swallowing discoordination is associated with frequent exacerbations of COPD
por: Nagami, Shinsuke, et al.
Publicado: (2017)

REI-1, a Novel Rab11 GEF with a SH3BP5 domain
por: Sakaguchi, Aisa, et al.
Publicado: (2016)

Structural determinants of Rab11 activation by the guanine nucleotide exchange factor SH3BP5
por: Jenkins, Meredith L., et al.
Publicado: (2018)

The emerging role of autophagy in peroxisome dynamics and lipid metabolism of phyllosphere microorganisms
por: Oku, Masahide, et al.
Publicado: (2014)

SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization
por: Antas, Pedro, et al.
Publicado: (2019)

Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells
por: Li, Minjing, et al.
Publicado: (2019)

SH3BP1 Regulates Melanoma Progression Through Race1/Wace2 Signaling Pathway
por: Sun, Ting, et al.
Publicado: (2023)

Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis
por: Marchesan, Julie Teresa, et al.
Publicado: (2013)

Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex
por: Elbediwy, Ahmed, et al.
Publicado: (2012)

SH3BP4, a novel pigmentation gene, is inversely regulated by miR-125b and MITF
por: Kim, Kyu-Han, et al.
Publicado: (2017)

Carbohydrate‐induced weight gain models for diabetes research: Contribution of incretins and parasympathetic signal
por: Seino, Yusuke, et al.
Publicado: (2020)

Viral infections in patients with an acute exacerbation of idiopathic interstitial pneumonia
por: Ushiki, Atsuhito, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5r7vsadtdjmu9rdf6o81l1vdkn