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Hyperglycemia Promotes K-Ras-Induced Lung Tumorigenesis through BASCs Amplification
Oncogenic K-Ras represents the most common molecular change in human lung adenocarcinomas, the major histologic subtype of non–small cell lung cancer (NSCLC). The presence of K-Ras mutation is associated with a poor prognosis, but no effective treatment strategies are available for K-Ras -mutant NSC...
Autores principales: | Micucci, Carla, Orciari, Silvia, Catalano, Alfonso |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140809/ https://www.ncbi.nlm.nih.gov/pubmed/25144301 http://dx.doi.org/10.1371/journal.pone.0105550 |
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