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Diffusion Tensor and Volumetric Magnetic Resonance Measures as Biomarkers of Brain Damage in a Small Animal Model of HIV

BACKGROUND: There are currently no widely accepted neuro-HIV small animal models. We wanted to validate the HIV-1 Transgenic rat (Tg) as an appropriate neuro-HIV model and then establish in vivo imaging biomarkers of neuropathology, within this model, using MR structural and diffusion tensor imaging...

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Detalles Bibliográficos
Autores principales:	Lentz, Margaret R., Peterson, Kristin L., Ibrahim, Wael G., Lee, Dianne E., Sarlls, Joelle, Lizak, Martin J., Maric, Dragan, Reid, William C., Hammoud, Dima A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140825/ https://www.ncbi.nlm.nih.gov/pubmed/25144656 http://dx.doi.org/10.1371/journal.pone.0105752

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