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Uracil-DNA Glycosylase Is Involved in DNA Demethylation and Required for Embryonic Development in the Zebrafish Embryo

Uracil-DNA glycosylase (Ung) is a component of the base excision repair process and has the ability to remove uracil from U:G mispairs in DNA. However, its implications in development of vertebrate embryos are poorly understood. In this study, we found that zebrafish uracil-DNA glycosylase a (Unga)...

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Detalles Bibliográficos
Autores principales: Wu, Di, Chen, Luxi, Sun, Qingrui, Wu, Xiaotong, Jia, Shunji, Meng, Anming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140902/
https://www.ncbi.nlm.nih.gov/pubmed/24739389
http://dx.doi.org/10.1074/jbc.M114.561019