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Pharmacological modulation of autophagy enhances Newcastle disease virus-mediated oncolysis in drug-resistant lung cancer cells

BACKGROUND: Oncolytic viruses represent a promising therapy against cancers with acquired drug resistance. However, low efficacy limits its clinical application. The objective of this study is to investigate whether pharmacologically modulating autophagy could enhance oncolytic Newcastle disease vir...

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Detalles Bibliográficos
Autores principales: Jiang, Ke, Li, Yingchun, Zhu, Qiumin, Xu, Jiansheng, Wang, Yupeng, Deng, Wuguo, Liu, Quentin, Zhang, Guirong, Meng, Songshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141091/
https://www.ncbi.nlm.nih.gov/pubmed/25078870
http://dx.doi.org/10.1186/1471-2407-14-551