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More ethical and more efficient clinical research: multiplex trial design
BACKGROUND: Today’s clinical research faces challenges such as a lack of clinical equipoise between treatment arms, reluctance in randomizing for multiple treatments simultaneously, inability to address interactions and increasingly restricted resources. Furthermore, many trials are biased by extens...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141104/ https://www.ncbi.nlm.nih.gov/pubmed/25125365 http://dx.doi.org/10.1186/1756-0500-7-530 |