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In silico analysis identifies novel restriction enzyme combinations that expand reduced representation bisulfite sequencing CpG coverage

BACKGROUND: Epigenetics is the study of gene expression changes that are not caused by changes in the deoxyribonucleic acid (DNA) sequence. DNA methylation is an epigenetic mark occurring in C–phosphate–G sites (CpGs) that leads to local or regional gene expression changes. Reduced-representation bi...

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Detalles Bibliográficos
Autores principales: Martinez-Arguelles, Daniel B, Lee, Sunghoon, Papadopoulos, Vassilios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141122/
https://www.ncbi.nlm.nih.gov/pubmed/25127888
http://dx.doi.org/10.1186/1756-0500-7-534