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Phospholipid binding residues of eukaryotic membrane-remodelling F-BAR domain proteins are conserved in Helicobacter pylori CagA

BACKGROUND: Cytotoxin associated gene product A (CagA) is an oncogenic protein secreted by the gastric bacterium Helicobacter pylori. Internalization of CagA by human epithelial cells occurs by an unknown mechanism that requires interaction with the host membrane lipid phosphatidylserine. FINDINGS:...

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Detalles Bibliográficos
Autor principal: Roujeinikova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141123/
https://www.ncbi.nlm.nih.gov/pubmed/25115379
http://dx.doi.org/10.1186/1756-0500-7-525