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Hammerhead ribozyme activity and oligonucleotide duplex stability in mixed solutions of water and organic compounds
Nucleic acids are useful for biomedical targeting and sensing applications in which the molecular environment is different from that of a dilute aqueous solution. In this study, the influence of various types of mixed solutions of water and water-soluble organic compounds on RNA was investigated by...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141205/ https://www.ncbi.nlm.nih.gov/pubmed/25161873 http://dx.doi.org/10.1016/j.fob.2014.06.009 |