Cargando…

Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice

Common functional polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, a key enzyme in folate and homocysteine metabolism, influence risk for a variety of complex disorders, including developmental, vascular, and neurological diseases. MTHFR deficiency is associated with elevation...

Descripción completa

Detalles Bibliográficos
Autores principales: Sontag, Jean-Marie, Wasek, Brandi, Taleski, Goce, Smith, Josephine, Arning, Erland, Sontag, Estelle, Bottiglieri, Teodoro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141544/
https://www.ncbi.nlm.nih.gov/pubmed/25202269
http://dx.doi.org/10.3389/fnagi.2014.00214