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Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice
Common functional polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, a key enzyme in folate and homocysteine metabolism, influence risk for a variety of complex disorders, including developmental, vascular, and neurological diseases. MTHFR deficiency is associated with elevation...
Autores principales: | Sontag, Jean-Marie, Wasek, Brandi, Taleski, Goce, Smith, Josephine, Arning, Erland, Sontag, Estelle, Bottiglieri, Teodoro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141544/ https://www.ncbi.nlm.nih.gov/pubmed/25202269 http://dx.doi.org/10.3389/fnagi.2014.00214 |
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