A diurnal serum lipid integrates hepatic lipogenesis and peripheral fatty acid utilization

Food intake increases the activity of hepatic de novo lipogenesis, which mediates the conversion of glucose to fats for storage or utilization. In mice, this program follows a circadian rhythm that peaks with nocturnal feeding(1,2) and is repressed by Rev-erbα/β and an HDAC3-containing complex(3–5)...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Sihao, Brown, Jonathan D., Stanya, Kristopher J., Homan, Edwin, Leidl, Mathias, Inouye, Karen, Bhargava, Prerna, Gangl, Matthew R., Dai, Lingling, Hatano, Ben, Hotamisligil, Gökhan S., Saghatelian, Alan, Plutzky, Jorge, Lee, Chih-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141623/
https://www.ncbi.nlm.nih.gov/pubmed/24153306
http://dx.doi.org/10.1038/nature12710

Ejemplares similares

Ejemplares similares