Synthesis and self-assembly behavior of a biodegradable and sustainable soybean oil-based copolymer nanomicelle

Herein, we report a novel amphiphilic biodegradable and sustainable soybean oil-based copolymer (SBC) prepared by grafting hydrophilic and biocompatible hydroxyethyl acrylate (HEA) polymeric segments onto the natural hydrophobic soybean oil chains. FTIR, H(1)-NMR, and GPC measurements have been used...

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Detalles Bibliográficos
Autores principales: Bao, Lixia, Bian, Longchun, Zhao, Mimi, Lei, Jingxin, Wang, Jiliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2014
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141661/
https://www.ncbi.nlm.nih.gov/pubmed/25170329
http://dx.doi.org/10.1186/1556-276X-9-391
Descripción
Sumario:Herein, we report a novel amphiphilic biodegradable and sustainable soybean oil-based copolymer (SBC) prepared by grafting hydrophilic and biocompatible hydroxyethyl acrylate (HEA) polymeric segments onto the natural hydrophobic soybean oil chains. FTIR, H(1)-NMR, and GPC measurements have been used to investigate the molecular structure of the obtained SBC macromolecules. Self-assembly behaviors of the prepared SBC in aqueous solution have also been extensively evaluated by fluorescence spectroscopy and transmission electron microscopy. The prepared SBC nanocarrier with the size range of 40 to 80 nm has a potential application in the biomedical field.

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