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Involvement of the chemokine CCL3 and the purinoceptor P2X7 in the spinal cord in paclitaxel-induced mechanical allodynia

BACKGROUND: Paclitaxel is an effective chemotherapeutic agent widely used for the treatment of solid tumors. The major dose-limiting toxicity of paclitaxel is peripheral neuropathy. The mechanisms underlying the development and maintenance of paclitaxel-induced peripheral neuropathy are still unclea...

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Detalles Bibliográficos
Autores principales:	Ochi-ishi, Ryutaro, Nagata, Kenichiro, Inoue, Tomoyuki, Tozaki-Saitoh, Hidetoshi, Tsuda, Makoto, Inoue, Kazuhide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141668/ https://www.ncbi.nlm.nih.gov/pubmed/25127716 http://dx.doi.org/10.1186/1744-8069-10-53

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