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Computational Investigation of Cholesterol Binding Sites on Mitochondrial VDAC

[Image: see text] The mitochondrial voltage-dependent anion channel (VDAC) allows passage of ions and metabolites across the mitochondrial outer membrane. Cholesterol binds mammalian VDAC, and we investigated the effects of binding to human VDAC1 with atomistic molecular dynamics simulations that to...

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Detalles Bibliográficos
Autores principales: Weiser, Brian P., Salari, Reza, Eckenhoff, Roderic G., Brannigan, Grace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141696/
https://www.ncbi.nlm.nih.gov/pubmed/25080204
http://dx.doi.org/10.1021/jp504516a