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Intermediate CAG Repeat Expansion in the ATXN2 Gene Is a Unique Genetic Risk Factor for ALS−A Systematic Review and Meta-Analysis of Observational Studies

Amyotrophic lateral sclerosis (ALS) is a rare degenerative condition of the motor neurons. Over 10% of ALS cases are linked to monogenic mutations, with the remainder thought to be due to other risk factors, including environmental factors, genetic polymorphisms, and possibly gene-environmental inte...

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Detalles Bibliográficos
Autores principales:	Wang, Ming-Dong, Gomes, James, Cashman, Neil R., Little, Julian, Krewski, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141758/ https://www.ncbi.nlm.nih.gov/pubmed/25148523 http://dx.doi.org/10.1371/journal.pone.0105534

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