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Comparative Analysis of Functional Metagenomic Annotation and the Mappability of Short Reads
To assess the functional capacities of microbial communities, including those inhabiting the human body, shotgun metagenomic reads are often aligned to a database of known genes. Such homology-based annotation practices critically rely on the assumption that short reads can map to orthologous genes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141809/ https://www.ncbi.nlm.nih.gov/pubmed/25148512 http://dx.doi.org/10.1371/journal.pone.0105776 |