Determinants of the Over-Anticoagulation Response during Warfarin Initiation Therapy in Asian Patients Based on Population Pharmacokinetic-Pharmacodynamic Analyses

To clarify pharmacokinetic-pharmacodynamic (PK-PD) factors associated with the over-anticoagulation response in Asians during warfarin induction therapy, population PK-PD analyses were conducted in an attempt to predict the time-courses of the plasma S-warfarin concentration, Cp(S), and coagulation...

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Detalles Bibliográficos
Autores principales: Ohara, Minami, Takahashi, Harumi, Lee, Ming Ta Michael, Wen, Ming-Shien, Lee, Tsong-Hai, Chuang, Hui-Ping, Luo, Chen-Hui, Arima, Aki, Onozuka, Akiko, Nagai, Rui, Shiomi, Mari, Mihara, Kiyoshi, Morita, Takashi, Chen, Yuan-Tsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141831/
https://www.ncbi.nlm.nih.gov/pubmed/25148255
http://dx.doi.org/10.1371/journal.pone.0105891

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