Hypertension and Hyperglycemia Synergize to Cause Incipient Renal Tubular Alterations Resulting in Increased NGAL Urinary Excretion in Rats

BACKGROUND: Hypertension and diabetes are the two leading causes of chronic kidney disease (CKD) eventually leading to end stage renal disease (ESRD) and the need of renal replacement therapy. Mortality among CKD and ESRD patients is high, mostly due to cardiovascular events. New early markers of ri...

Descripción completa

Detalles Bibliográficos
Autores principales: Blázquez-Medela, Ana M., García-Sánchez, Omar, Blanco-Gozalo, Víctor, Quiros, Yaremi, Montero, María J., Martínez-Salgado, Carlos, López-Novoa, José M., López-Hernández, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141836/
https://www.ncbi.nlm.nih.gov/pubmed/25148248
http://dx.doi.org/10.1371/journal.pone.0105988