Cargando…
A 40 kDa protein of the inner membrane is the mitochondrial calcium uniporter
Mitochondrial Ca(2+) homeostasis plays a key role in the regulation of aerobic metabolism and cell survival(1), but the molecular identity of the Ca(2+) channel, the mitochondrial calcium uniporter(2), was still unknown. We have identified in silico a protein (denominated MCU) that shares tissue dis...
Autores principales: | De Stefani, Diego, Raffaello, Anna, Teardo, Enrico, Szabò, Ildikò, Rizzuto, Rosario |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141877/ https://www.ncbi.nlm.nih.gov/pubmed/21685888 http://dx.doi.org/10.1038/nature10230 |
Ejemplares similares
-
MICU1 and MICU2 Finely Tune the Mitochondrial Ca(2+) Uniporter by Exerting Opposite Effects on MCU Activity
por: Patron, Maria, et al.
Publicado: (2014) -
Overexpression of Mitochondrial Calcium Uniporter Causes Neuronal Death
por: Granatiero, Veronica, et al.
Publicado: (2019) -
Data on physicochemical properties of LPEI 25 kDa, PEI“Max” 40 kDa and PEIpro™
por: Delafosse, Laurence, et al.
Publicado: (2016) -
The Mitochondrial Calcium Uniporter (MCU): Molecular Identity and Role in Human Diseases
por: D’Angelo, Donato, et al.
Publicado: (2023) -
Structure, Activity Regulation, and Role of the Mitochondrial Calcium Uniporter in Health and Disease
por: Mammucari, Cristina, et al.
Publicado: (2017)