Conjugated bile acids promote cholangiocarcinoma cell invasive growth through activation of sphingosine 1-phosphate receptor 2

Cholangiocarcinoma (CCA) is an often fatal primary malignancy of the intra- and extrahepatic biliary tract that is commonly associated with chronic cholestasis and significantly elevated levels of primary and conjugated bile acids (CBAs), which are correlated with bile duct obstruction (BDO). BDO ha...

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Detalles Bibliográficos
Autores principales: Liu, Runping, Zhao, Renping, Zhou, Xiqiao, Liang, Xiuyin, Campbell, Deanna JW, Zhang, Xiaoxuan, Zhang, Luyong, Shi, Ruihua, Wang, Guangji, Pandak, William M, Sirica, Alphonse E, Hylemon, Phillip B, Zhou, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Hepatobiliary Malignancies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141906/
https://www.ncbi.nlm.nih.gov/pubmed/24700501
http://dx.doi.org/10.1002/hep.27085

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