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P53 nuclear stabilization is associated with FHIT loss and younger age of onset in squamous cell carcinoma of oral tongue

BACKGROUND: Squamous cell carcinoma of tongue (SCCT) is expected to harbor unique clinico-pathological and molecular genetic features since a significant proportion of patients are young and exhibit no association with tobacco or alcohol. METHODS: We determined P53, epidermal growth factor receptor,...

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Detalles Bibliográficos
Autores principales: Adduri, Raju SR, Kotapalli, Viswakalyan, Gupta, Neha A, Gowrishankar, Swarnalata, Srinivasulu, Mukta, Ali, Mohammed Mujtaba, Rao, Subramanyeshwar, Uppin, Shantveer G, Nayak, Umanath K, Dhagam, Snehalatha, Chigurupati, Mohana Vamsy, Bashyam, Murali Dharan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4141988/
https://www.ncbi.nlm.nih.gov/pubmed/25152695
http://dx.doi.org/10.1186/1472-6890-14-37