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Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina
Background. Comorbid autoimmune diseases in MS patients have been studied extensively with controversial results. Moreover, no such data exists for Latin-American MS patients. Methods. We conducted a case-control study aimed to establish the prevalence of autoimmune disorders in a cohort of Argentin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142150/ https://www.ncbi.nlm.nih.gov/pubmed/25170425 http://dx.doi.org/10.1155/2014/828162 |
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author | Farez, Mauricio F. Balbuena Aguirre, María E. Varela, Francisco Köhler, Alejandro A. Correale, Jorge |
author_facet | Farez, Mauricio F. Balbuena Aguirre, María E. Varela, Francisco Köhler, Alejandro A. Correale, Jorge |
author_sort | Farez, Mauricio F. |
collection | PubMed |
description | Background. Comorbid autoimmune diseases in MS patients have been studied extensively with controversial results. Moreover, no such data exists for Latin-American MS patients. Methods. We conducted a case-control study aimed to establish the prevalence of autoimmune disorders in a cohort of Argentinean MS patients. Results. There were no significant differences in autoimmune disease prevalence in MS patients with respect to controls. The presence of one or more autoimmune disorders did not increase risk of MS (OR 0.85, 95% CI 0.6–1.3). Discussion. Our results indicate absence of increased comorbid autoimmune disease prevalence in MS patients, as well as of increased risk of MS in patients suffering from other autoimmune disorders. |
format | Online Article Text |
id | pubmed-4142150 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-41421502014-08-28 Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina Farez, Mauricio F. Balbuena Aguirre, María E. Varela, Francisco Köhler, Alejandro A. Correale, Jorge Mult Scler Int Research Article Background. Comorbid autoimmune diseases in MS patients have been studied extensively with controversial results. Moreover, no such data exists for Latin-American MS patients. Methods. We conducted a case-control study aimed to establish the prevalence of autoimmune disorders in a cohort of Argentinean MS patients. Results. There were no significant differences in autoimmune disease prevalence in MS patients with respect to controls. The presence of one or more autoimmune disorders did not increase risk of MS (OR 0.85, 95% CI 0.6–1.3). Discussion. Our results indicate absence of increased comorbid autoimmune disease prevalence in MS patients, as well as of increased risk of MS in patients suffering from other autoimmune disorders. Hindawi Publishing Corporation 2014 2014-08-06 /pmc/articles/PMC4142150/ /pubmed/25170425 http://dx.doi.org/10.1155/2014/828162 Text en Copyright © 2014 Mauricio F. Farez et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Farez, Mauricio F. Balbuena Aguirre, María E. Varela, Francisco Köhler, Alejandro A. Correale, Jorge Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina |
title | Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina |
title_full | Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina |
title_fullStr | Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina |
title_full_unstemmed | Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina |
title_short | Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina |
title_sort | autoimmune disease prevalence in a multiple sclerosis cohort in argentina |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142150/ https://www.ncbi.nlm.nih.gov/pubmed/25170425 http://dx.doi.org/10.1155/2014/828162 |
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