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Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina

Background. Comorbid autoimmune diseases in MS patients have been studied extensively with controversial results. Moreover, no such data exists for Latin-American MS patients. Methods. We conducted a case-control study aimed to establish the prevalence of autoimmune disorders in a cohort of Argentin...

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Autores principales: Farez, Mauricio F., Balbuena Aguirre, María E., Varela, Francisco, Köhler, Alejandro A., Correale, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142150/
https://www.ncbi.nlm.nih.gov/pubmed/25170425
http://dx.doi.org/10.1155/2014/828162
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author Farez, Mauricio F.
Balbuena Aguirre, María E.
Varela, Francisco
Köhler, Alejandro A.
Correale, Jorge
author_facet Farez, Mauricio F.
Balbuena Aguirre, María E.
Varela, Francisco
Köhler, Alejandro A.
Correale, Jorge
author_sort Farez, Mauricio F.
collection PubMed
description Background. Comorbid autoimmune diseases in MS patients have been studied extensively with controversial results. Moreover, no such data exists for Latin-American MS patients. Methods. We conducted a case-control study aimed to establish the prevalence of autoimmune disorders in a cohort of Argentinean MS patients. Results. There were no significant differences in autoimmune disease prevalence in MS patients with respect to controls. The presence of one or more autoimmune disorders did not increase risk of MS (OR 0.85, 95% CI 0.6–1.3). Discussion. Our results indicate absence of increased comorbid autoimmune disease prevalence in MS patients, as well as of increased risk of MS in patients suffering from other autoimmune disorders.
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spelling pubmed-41421502014-08-28 Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina Farez, Mauricio F. Balbuena Aguirre, María E. Varela, Francisco Köhler, Alejandro A. Correale, Jorge Mult Scler Int Research Article Background. Comorbid autoimmune diseases in MS patients have been studied extensively with controversial results. Moreover, no such data exists for Latin-American MS patients. Methods. We conducted a case-control study aimed to establish the prevalence of autoimmune disorders in a cohort of Argentinean MS patients. Results. There were no significant differences in autoimmune disease prevalence in MS patients with respect to controls. The presence of one or more autoimmune disorders did not increase risk of MS (OR 0.85, 95% CI 0.6–1.3). Discussion. Our results indicate absence of increased comorbid autoimmune disease prevalence in MS patients, as well as of increased risk of MS in patients suffering from other autoimmune disorders. Hindawi Publishing Corporation 2014 2014-08-06 /pmc/articles/PMC4142150/ /pubmed/25170425 http://dx.doi.org/10.1155/2014/828162 Text en Copyright © 2014 Mauricio F. Farez et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Farez, Mauricio F.
Balbuena Aguirre, María E.
Varela, Francisco
Köhler, Alejandro A.
Correale, Jorge
Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina
title Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina
title_full Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina
title_fullStr Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina
title_full_unstemmed Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina
title_short Autoimmune Disease Prevalence in a Multiple Sclerosis Cohort in Argentina
title_sort autoimmune disease prevalence in a multiple sclerosis cohort in argentina
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142150/
https://www.ncbi.nlm.nih.gov/pubmed/25170425
http://dx.doi.org/10.1155/2014/828162
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