Cephalexin Induced Cholestatic Jaundice

Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including el...

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Autores principales: Agrawal, Abhinav, Rao, Mana, Jasdanwala, Sarfaraz, Mathur, Ajay, Eng, Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142286/
https://www.ncbi.nlm.nih.gov/pubmed/25180107
http://dx.doi.org/10.1155/2014/260743
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author Agrawal, Abhinav
Rao, Mana
Jasdanwala, Sarfaraz
Mathur, Ajay
Eng, Margaret
author_facet Agrawal, Abhinav
Rao, Mana
Jasdanwala, Sarfaraz
Mathur, Ajay
Eng, Margaret
author_sort Agrawal, Abhinav
collection PubMed
description Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including elevated liver function tests (LFTs) after taking cephalexin and showed improvement on removal of the offending agent. During this time he was symptomatically treated with cholestyramine. Complete resolution of LFTs was seen in four weeks. Cephalexin induced cholestasis is rare and hence requires a high degree of clinical suspicion for prompt diagnosis and treatment.
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spelling pubmed-41422862014-09-01 Cephalexin Induced Cholestatic Jaundice Agrawal, Abhinav Rao, Mana Jasdanwala, Sarfaraz Mathur, Ajay Eng, Margaret Case Rep Gastrointest Med Case Report Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including elevated liver function tests (LFTs) after taking cephalexin and showed improvement on removal of the offending agent. During this time he was symptomatically treated with cholestyramine. Complete resolution of LFTs was seen in four weeks. Cephalexin induced cholestasis is rare and hence requires a high degree of clinical suspicion for prompt diagnosis and treatment. Hindawi Publishing Corporation 2014 2014-08-07 /pmc/articles/PMC4142286/ /pubmed/25180107 http://dx.doi.org/10.1155/2014/260743 Text en Copyright © 2014 Abhinav Agrawal et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Agrawal, Abhinav
Rao, Mana
Jasdanwala, Sarfaraz
Mathur, Ajay
Eng, Margaret
Cephalexin Induced Cholestatic Jaundice
title Cephalexin Induced Cholestatic Jaundice
title_full Cephalexin Induced Cholestatic Jaundice
title_fullStr Cephalexin Induced Cholestatic Jaundice
title_full_unstemmed Cephalexin Induced Cholestatic Jaundice
title_short Cephalexin Induced Cholestatic Jaundice
title_sort cephalexin induced cholestatic jaundice
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142286/
https://www.ncbi.nlm.nih.gov/pubmed/25180107
http://dx.doi.org/10.1155/2014/260743
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