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Donor Haplotype B of NK KIR Receptor Reduces the Relapse Risk in HLA-Identical Sibling Hematopoietic Stem Cell Transplantation of AML Patients

Successful allogeneic hematopoietic stem cell transplantation (HSCT) depends not only on good HLA match but also on T-cell mediated graft-versus-leukemia (GvL) effect. Natural killer (NK) cells are able to kill malignant cells by receiving activation signal from the killer-cell immunoglobulin-like r...

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Detalles Bibliográficos
Autores principales:	Impola, Ulla, Turpeinen, Hannu, Alakulppi, Noora, Linjama, Tiina, Volin, Liisa, Niittyvuopio, Riitta, Partanen, Jukka, Koskela, Satu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2014
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142321/ https://www.ncbi.nlm.nih.gov/pubmed/25202311 http://dx.doi.org/10.3389/fimmu.2014.00405

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