Phosphodiesterase (PDE)-4 Inhibitors and COPD Correlation with Cancer

A new drug for chronic obstructive pulmonary disease has been recently added as a treatment for certain patients. However, new evidences indicate that there might be a connection with lung cancer. It is known that smoking is a major factor that induces chronic pulmonary disease and smoking is associ...

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Detalles Bibliográficos
Autores principales: Organtzis, John, Lampaki, Sofia, Zarogoulidis, Paul, Huang, Haidong, Li, Qiang, Papaiwannou, Antonis, Syrigos, Konstantinos, Porpodis, Konstantinos, Tsiouda, Theodora, Hohenforst-Schmidt, Wolfgang, Trakada, Georgia, Walter, Robert Fred Henry, Makrantonaki, Dimitra, Pitsiou, Georgia, Kioumis, Ioannis, Zarogoulidis, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142323/
https://www.ncbi.nlm.nih.gov/pubmed/25157272
http://dx.doi.org/10.7150/jca.9730
Descripción
Sumario:A new drug for chronic obstructive pulmonary disease has been recently added as a treatment for certain patients. However, new evidences indicate that there might be a connection with lung cancer. It is known that smoking is a major factor that induces chronic pulmonary disease and smoking is associated with lung cancer. The level of connection between phosphodiesterase (PDE)-4 inhibitors and lung cancer will be discussed based on current studies. A comment will be made whether lung cancer is induced to patients receiving phosphodiesterase (PDE)-4 inhibitors from the drug or former smoking habit.

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