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Peroxisome proliferator-activated receptor gamma (PPARG) modulates free fatty acid receptor 1 (FFAR1) dependent insulin secretion in humans

Genetic variation in FFAR1 modulates insulin secretion dependent on non-esterified fatty acid (NEFA) concentrations. We previously demonstrated lower insulin secretion in minor allele carriers of PPARG Pro12Ala in high-NEFA environment, but the mode of action could not been revealed. We tested if th...

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Detalles Bibliográficos
Autores principales:	Wagner, Robert, Hieronimus, Anja, Lamprinou, Apostolia, Heni, Martin, Hatziagelaki, Erifili, Ullrich, Susanne, Stefan, Norbert, Staiger, Harald, Häring, Hans-Ulrich, Fritsche, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142395/ https://www.ncbi.nlm.nih.gov/pubmed/25161890 http://dx.doi.org/10.1016/j.molmet.2014.07.001

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