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Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesity()

Therapies that improve leptin sensitivity have potential as an alternative treatment approach against obesity and related comorbidities. We investigated the effects of Socs3 gene ablation in different mouse models to understand the role of SOCS3 in the regulation of leptin sensitivity, diet-induced...

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Detalles Bibliográficos
Autores principales:	Pedroso, João A.B., Buonfiglio, Daniella C., Cardinali, Lais I., Furigo, Isadora C., Ramos-Lobo, Angela M., Tirapegui, Julio, Elias, Carol F., Donato, Jose
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142399/ https://www.ncbi.nlm.nih.gov/pubmed/25161884 http://dx.doi.org/10.1016/j.molmet.2014.06.001

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