Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity

The vagal afferent pathway senses hormones released from the gut in response to nutritional cues and relays these signals to the brain. We tested the hypothesis that leptin resistance in vagal afferent neurons (VAN) is responsible for the onset of hyperphagia by developing a novel conditional knocko...

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Detalles Bibliográficos
Autores principales: de Lartigue, Guillaume, Ronveaux, Charlotte C., Raybould, Helen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142400/
https://www.ncbi.nlm.nih.gov/pubmed/25161883
http://dx.doi.org/10.1016/j.molmet.2014.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142400/
https://www.ncbi.nlm.nih.gov/pubmed/25161883
http://dx.doi.org/10.1016/j.molmet.2014.06.003

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