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Deletion of leptin signaling in vagal afferent neurons results in hyperphagia and obesity
The vagal afferent pathway senses hormones released from the gut in response to nutritional cues and relays these signals to the brain. We tested the hypothesis that leptin resistance in vagal afferent neurons (VAN) is responsible for the onset of hyperphagia by developing a novel conditional knocko...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142400/ https://www.ncbi.nlm.nih.gov/pubmed/25161883 http://dx.doi.org/10.1016/j.molmet.2014.06.003 |