CEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targets

Transcription factor CEBPA has been widely studied for its involvement in hematopoietic cell differentiation and causal role in hematological malignancies. We demonstrate here that it also performs a causal role in cytokine-induced apoptosis of pancreas β cells. Treatment of two mouse pancreatic α a...

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Detalles Bibliográficos
Autores principales: Barbagallo, Davide, Condorelli, Angelo Giuseppe, Piro, Salvatore, Parrinello, Nunziatina, Fløyel, Tina, Ragusa, Marco, Rabuazzo, Agata Maria, Størling, Joachim, Purrello, Francesco, Di Pietro, Cinzia, Purrello, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142607/
https://www.ncbi.nlm.nih.gov/pubmed/24943845
http://dx.doi.org/10.1091/mbc.E14-02-0703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142607/
https://www.ncbi.nlm.nih.gov/pubmed/24943845
http://dx.doi.org/10.1091/mbc.E14-02-0703

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