Cargando…
E-cadherin phosphorylation occurs during its biosynthesis to promote its cell surface stability and adhesion
E-cadherin is highly phosphorylated within its β-catenin–binding region, and this phosphorylation increases its affinity for β-catenin in vitro. However, the identification of key serines responsible for most cadherin phosphorylation and the adhesive consequences of modification at such serines have...
Autores principales: | McEwen, Abbye E., Maher, Meghan T., Mo, Rigen, Gottardi, Cara J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142610/ https://www.ncbi.nlm.nih.gov/pubmed/24966173 http://dx.doi.org/10.1091/mbc.E14-01-0690 |
Ejemplares similares
-
β-Catenin Phosphorylated at Serine 45 Is Spatially Uncoupled from β-Catenin Phosphorylated in the GSK3 Domain: Implications for Signaling
por: Maher, Meghan T., et al.
Publicado: (2010) -
Activity of the β-catenin phosphodestruction complex at cell–cell contacts is enhanced by cadherin-based adhesion
por: Maher, Meghan T., et al.
Publicado: (2009) -
E-Cadherin Suppresses Cellular Transformation by Inhibiting β-Catenin Signaling in an Adhesion-Independent Manner
por: Gottardi, Cara J., et al.
Publicado: (2001) -
Cadherin exits the junction by switching its adhesive bond
por: Hong, Soonjin, et al.
Publicado: (2011) -
Beyond the Blood: CSF-Derived cfDNA for Diagnosis and Characterization of CNS Tumors
por: McEwen, Abbye E., et al.
Publicado: (2020)