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Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity

Oxidative stress is a consequence of an imbalance between reactive oxygen species (ROS) production and the ability of the cytoprotective system to detoxify the reactive intermediates. The tumor suppressor promyelocytic leukemia protein (PML) functions as a stress sensor. Loss of PML results in impai...

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Detalles Bibliográficos
Autores principales: Guo, Shuang, Cheng, Xiwen, Lim, Jun-Hee, Liu, Yu, Kao, Hung-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142619/
https://www.ncbi.nlm.nih.gov/pubmed/24943846
http://dx.doi.org/10.1091/mbc.E13-11-0692