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Control of antioxidative response by the tumor suppressor protein PML through regulating Nrf2 activity
Oxidative stress is a consequence of an imbalance between reactive oxygen species (ROS) production and the ability of the cytoprotective system to detoxify the reactive intermediates. The tumor suppressor promyelocytic leukemia protein (PML) functions as a stress sensor. Loss of PML results in impai...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142619/ https://www.ncbi.nlm.nih.gov/pubmed/24943846 http://dx.doi.org/10.1091/mbc.E13-11-0692 |