Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming

In the early twentieth century, Otto Heinrich Warburg described an elevated rate of glycolysis occurring in cancer cells, even in the presence of atmospheric oxygen (the Warburg effect). Despite the inefficiency of ATP generation through glycolysis, the breakdown of glucose into lactate provides can...

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Detalles Bibliográficos
Autores principales: Zwaans, Bernadette M. M., Lombard, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142723/
https://www.ncbi.nlm.nih.gov/pubmed/25085992
http://dx.doi.org/10.1242/dmm.016287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142723/
https://www.ncbi.nlm.nih.gov/pubmed/25085992
http://dx.doi.org/10.1242/dmm.016287

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