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Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis

In recent years there has been an increasing awareness of the role of P2X7, a receptor for extracellular ATP, in modulating physiopathological mechanisms in the central nervous system. In particular, P2X7 has been shown to be implicated in neuropsychiatry, chronic pain, neurodegeneration and neuroin...

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Detalles Bibliográficos
Autores principales: Apolloni, Savina, Amadio, Susanna, Parisi, Chiara, Matteucci, Alessandra, Potenza, Rosa L., Armida, Monica, Popoli, Patrizia, D’Ambrosi, Nadia, Volonté, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142730/
https://www.ncbi.nlm.nih.gov/pubmed/25038061
http://dx.doi.org/10.1242/dmm.017038