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Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis
In recent years there has been an increasing awareness of the role of P2X7, a receptor for extracellular ATP, in modulating physiopathological mechanisms in the central nervous system. In particular, P2X7 has been shown to be implicated in neuropsychiatry, chronic pain, neurodegeneration and neuroin...
Autores principales: | Apolloni, Savina, Amadio, Susanna, Parisi, Chiara, Matteucci, Alessandra, Potenza, Rosa L., Armida, Monica, Popoli, Patrizia, D’Ambrosi, Nadia, Volonté, Cinzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142730/ https://www.ncbi.nlm.nih.gov/pubmed/25038061 http://dx.doi.org/10.1242/dmm.017038 |
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