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Robust circadian rhythms in organoid cultures from PERIOD2::LUCIFERASE mouse small intestine
Disruption of circadian rhythms is a risk factor for several human gastrointestinal (GI) diseases, ranging from diarrhea to ulcers to cancer. Four-dimensional tissue culture models that faithfully mimic the circadian clock of the GI epithelium would provide an invaluable tool to understand circadian...
Autores principales: | Moore, Sean R., Pruszka, Jill, Vallance, Jefferson, Aihara, Eitaro, Matsuura, Toru, Montrose, Marshall H., Shroyer, Noah F., Hong, Christian I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142732/ https://www.ncbi.nlm.nih.gov/pubmed/24997189 http://dx.doi.org/10.1242/dmm.014399 |
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