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Synthesis of trifluoromethyl-substituted pyrazolo[4,3-c]pyridines – sequential versus multicomponent reaction approach

A straightforward synthesis of 6-substituted 1-phenyl-3-trifluoromethyl-1H-pyrazolo[4,3-c]pyridines and the corresponding 5-oxides is presented. Hence, microwave-assisted treatment of 5-chloro-1-phenyl-3-trifluoromethylpyrazole-4-carbaldehyde with various terminal alkynes in the presence of tert-but...

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Detalles Bibliográficos
Autores principales:	Palka, Barbara, Di Capua, Angela, Anzini, Maurizio, Vilkauskaité, Gyté, Šačkus, Algirdas, Holzer, Wolfgang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2014
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142841/ https://www.ncbi.nlm.nih.gov/pubmed/25161734 http://dx.doi.org/10.3762/bjoc.10.183

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