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Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia

Simultaneous proptosis and facial palsy as the clinical presentation of childhoodAcute Myeloid Leukaemia (AML) is very rare. To date, no case have beenreported anywhere to the best of our knowledge. Extra medullary leukemic deposits or Granulocytic Sarcoma (GS) is a rare manifestation in about 3% of...

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Autores principales: Takhenchangbam, Dhaneshor Sharma, Laishram, Rajesh Singh, Thoudem, Tomcha Singh, Sunita, Akoijam, Imchen, Lanu Tiameren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Research Center, Shahid Beheshti University of Medical Sciences 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142910/
https://www.ncbi.nlm.nih.gov/pubmed/25250110
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author Takhenchangbam, Dhaneshor Sharma
Laishram, Rajesh Singh
Thoudem, Tomcha Singh
Sunita, Akoijam
Imchen, Lanu Tiameren
author_facet Takhenchangbam, Dhaneshor Sharma
Laishram, Rajesh Singh
Thoudem, Tomcha Singh
Sunita, Akoijam
Imchen, Lanu Tiameren
author_sort Takhenchangbam, Dhaneshor Sharma
collection PubMed
description Simultaneous proptosis and facial palsy as the clinical presentation of childhoodAcute Myeloid Leukaemia (AML) is very rare. To date, no case have beenreported anywhere to the best of our knowledge. Extra medullary leukemic deposits or Granulocytic Sarcoma (GS) is a rare manifestation in about 3% of childhood AML, 9.3% of GS manifested as orbit deposits causing proptosis in one or both eyes. CNS infiltration or acute otomastoiditis subsequent to leukemic infiltration of the temporal bone may be implicated with facial paralysis. We are here with reporting the case in a 3-year-old boy who presented with proptosis and facial palsy in a case of AML. The purpose of reporting this case is to emphasize the need of examining the peripheral blood and bone marrow in children presenting as proptosis and facial palsy for early diagnosis of childhood AML.
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spelling pubmed-41429102014-09-23 Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia Takhenchangbam, Dhaneshor Sharma Laishram, Rajesh Singh Thoudem, Tomcha Singh Sunita, Akoijam Imchen, Lanu Tiameren Iran J Cancer Prev Case Report Simultaneous proptosis and facial palsy as the clinical presentation of childhoodAcute Myeloid Leukaemia (AML) is very rare. To date, no case have beenreported anywhere to the best of our knowledge. Extra medullary leukemic deposits or Granulocytic Sarcoma (GS) is a rare manifestation in about 3% of childhood AML, 9.3% of GS manifested as orbit deposits causing proptosis in one or both eyes. CNS infiltration or acute otomastoiditis subsequent to leukemic infiltration of the temporal bone may be implicated with facial paralysis. We are here with reporting the case in a 3-year-old boy who presented with proptosis and facial palsy in a case of AML. The purpose of reporting this case is to emphasize the need of examining the peripheral blood and bone marrow in children presenting as proptosis and facial palsy for early diagnosis of childhood AML. Cancer Research Center, Shahid Beheshti University of Medical Sciences 2013 /pmc/articles/PMC4142910/ /pubmed/25250110 Text en © 2014 Cancer Research Center, Shahid Beheshti University of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Case Report
Takhenchangbam, Dhaneshor Sharma
Laishram, Rajesh Singh
Thoudem, Tomcha Singh
Sunita, Akoijam
Imchen, Lanu Tiameren
Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia
title Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia
title_full Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia
title_fullStr Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia
title_full_unstemmed Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia
title_short Proptosis and Facial Palsy as an Unusual Clinical Presentation of Acute Myeloid Leukemia
title_sort proptosis and facial palsy as an unusual clinical presentation of acute myeloid leukemia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142910/
https://www.ncbi.nlm.nih.gov/pubmed/25250110
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