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An interferon-beta promoter reporter assay for high throughput identification of compounds against multiple RNA viruses
Virus infection of host cells is sensed by innate pattern recognition receptors (PRRs) and induces production of type I interferons (IFNs) and other inflammatory cytokines. These cytokines orchestrate the elimination of the viruses but are occasionally detrimental to the hosts. The outcomes and path...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143146/ https://www.ncbi.nlm.nih.gov/pubmed/24792753 http://dx.doi.org/10.1016/j.antiviral.2014.04.010 |