Cargando…

Psychosocial Predictors of Non-Adherence and Treatment Failure in a Large Scale Multi-National Trial of Antiretroviral Therapy for HIV: Data from the ACTG A5175/PEARLS Trial

BACKGROUND: PEARLS, a large scale trial of antiretroviral therapy (ART) for HIV (n = 1,571, 9 countries, 4 continents), found that a once-daily protease inhibitor (PI) based regimen (ATV+DDI+FTC), but not a once-daily non-nucleoside reverse transcriptase inhibitor/nucleoside reverse transcriptase in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Safren, Steven A., Biello, Katie B., Smeaton, Laura, Mimiaga, Matthew J., Walawander, Ann, Lama, Javier R., Rana, Aadia, Nyirenda, Mulinda, Kayoyo, Virginia M., Samaneka, Wadzanai, Joglekar, Anjali, Celentano, David, Martinez, Ana, Remmert, Jocelyn E., Nair, Aspara, Lalloo, Umesh G., Kumarasamy, Nagalingeswaran, Hakim, James, Campbell, Thomas B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143224/ https://www.ncbi.nlm.nih.gov/pubmed/25153084 http://dx.doi.org/10.1371/journal.pone.0104178

Ejemplares similares

Outcomes among HIV-1 Infected Individuals First Starting Antiretroviral Therapy with Concurrent Active TB or Other AIDS-Defining Disease
por: Périssé, André R. S., et al.
Publicado: (2013)

Complete genome sequence of Sulfurospirillum deleyianum type strain (5175(T))
por: Sikorski, Johannes, et al.
Publicado: (2010)

Third‐line antiretroviral therapy, including raltegravir (RAL), darunavir (DRV/r) and/or etravirine (ETR), is well tolerated and achieves durable virologic suppression over 144 weeks in resource‐limited settings: ACTG A5288 strategy trial
por: Avihingsanon, Anchalee, et al.
Publicado: (2022)

Frequency of Antiretroviral Resistance Mutations among Infants Exposed to Single-Dose Nevirapine and Short Course Maternal Antiretroviral Regimens: ACTG A5207
por: Hitti, Jane, et al.
Publicado: (2014)

Continuing or adding IL-2 in patients treated with antiretroviral therapy (ACTG Protocol A5051, a rollover trial of ACTG Protocol A328)
por: Bosch, Ronald J, et al.
Publicado: (2010)

A Pre-Exposure Prophylaxis Adherence Intervention (LifeSteps) for Young Men Who Have Sex With Men: Protocol for a Pilot Randomized Controlled Trial
por: Biello, Katie B, et al.
Publicado: (2019)

Gender-Specific Related Factors for Suicidal Ideation During COVID-19 Pandemic Lockdown Among 5,175 Chinese Adolescents
por: Zhu, Jin, et al.
Publicado: (2022)

Nucleotide- and Protein-Dependent Functions of Actg1
por: Sundby, Lauren J., et al.
Publicado: (2022)

Economic modeling of the combined effects of HIV-disease, cholesterol and lipoatrophy based on ACTG 5142 trial data
por: Simpson, Kit N, et al.
Publicado: (2011)

Higher Dose Oral Fluconazole for the Treatment of AIDS-related Cryptococcal Meningitis (HIFLAC)—report of A5225, a multicentre, phase I/II, two-stage, dose-finding, safety, tolerability and efficacy randomised, amphotericin B-controlled trial of the AIDS Clinical Trials Group
por: Lalloo, Umesh G., et al.
Publicado: (2023)

Multiple syndemic psychosocial factors are associated with reduced engagement in HIV care among a multinational, online sample of HIV-infected MSM in Latin America
por: Biello, Katie B., et al.
Publicado: (2016)

Expanding the genotypic spectrum of ACTG2-related visceral myopathy
por: James, Kiely N., et al.
Publicado: (2021)

Autosomal Recessive ACTG2-Related Visceral Myopathy in Brothers
por: Mori, Mari, et al.
Publicado: (2022)

A randomized clinical efficacy trial of a psychosocial intervention to strengthen self-acceptance and reduce HIV risk for MSM in India: study protocol
por: Mimiaga, Matthew J., et al.
Publicado: (2018)

A minimal monitoring approach for the treatment of hepatitis C virus infection (ACTG A5360 [MINMON]): a phase 4, open-label, single-arm trial
por: Solomon, Sunil S, et al.
Publicado: (2022)

Project LifeSkills - a randomized controlled efficacy trial of a culturally tailored, empowerment-based, and group-delivered HIV prevention intervention for young transgender women: study protocol
por: Kuhns, Lisa M., et al.
Publicado: (2017)

Treating Depression and Adherence (CBT-AD) in Patients with HIV in Care: A Three-arm Randomized Controlled Trial
por: Safren, Steven A., et al.
Publicado: (2016)

Strengthening resilience to reduce HIV risk in Indian MSM: a multicity, randomised, clinical efficacy trial
por: Safren, Steven A, et al.
Publicado: (2021)

ACTG1 and TLR3 are biomarkers for alcohol-associated hepatocellular carcinoma
por: Gao, Bing, et al.
Publicado: (2019)

RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma
por: Yan, Yingcai, et al.
Publicado: (2019)

ACTG2 Variants in Pediatric Chronic Intestinal Pseudo-obstruction With Megacystis
por: Hahn, Jong Woo, et al.
Publicado: (2022)

A randomized controlled efficacy trial of behavioral activation for concurrent stimulant use and sexual risk for HIV acquisition among MSM: project IMPACT study protocol
por: Mimiaga, Matthew J., et al.
Publicado: (2018)

Obsessive–compulsive symptoms in ACTG1-associated Baraitser-Winter cerebrofrontofacial syndrome
por: Göbel, Theresa, et al.
Publicado: (2022)

Human Immunodeficiency Virus-1 Sequence Changes and Drug Resistance Mutation Among Virologic Failures of Lopinavir/Ritonavir Monotherapy: AIDS Clinical Trials Group Protocol A5230
por: Vardhanabhuti, Saran, et al.
Publicado: (2016)

A Mobile-Based App (MyChoices) to Increase Uptake of HIV Testing and Pre-Exposure Prophylaxis by Young Men Who Have Sex With Men: Protocol for a Pilot Randomized Controlled Trial
por: Biello, Katie B, et al.
Publicado: (2019)

Potential Impact of Targeted HIV Pre-Exposure Prophylaxis Uptake Among Male Sex Workers
por: Goedel, William C., et al.
Publicado: (2020)

A Novel Actin mRNA Splice Variant Regulates ACTG1 Expression
por: Drummond, Meghan C., et al.
Publicado: (2013)

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma
por: Rainger, Joe, et al.
Publicado: (2017)

Genomic Amplification and Functional Dependency of the Gamma Actin Gene ACTG1 in Uterine Cancer
por: Richter, Camden, et al.
Publicado: (2020)

Changes in lipidomic profile by anti-retroviral treatment regimen: An ACTG 5257 ancillary study
por: Chaudhary, Ninad S., et al.
Publicado: (2021)

Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1
por: Luo, Jun-qi, et al.
Publicado: (2023)

837 Early Goal Directed Therapy for Acute Bacterial Meningitis in Malawian Adults
por: Wall, Emma, et al.
Publicado: (2014)

Efficacy and Safety of Three Antiretroviral Regimens for Initial Treatment of HIV-1: A Randomized Clinical Trial in Diverse Multinational Settings
por: Campbell, Thomas B., et al.
Publicado: (2012)

De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome
por: Rivière, Jean-Baptiste, et al.
Publicado: (2012)

Pseudo-obstruction–inducing ACTG2(R257C) alters actin organization and function
por: Hashmi, Sohaib Khalid, et al.
Publicado: (2020)

Study protocol for an efficacy trial of the “PrEP for Health” intervention to increase HIV PrEP use among people who inject drugs
por: Bazzi, Angela R., et al.
Publicado: (2023)

Design and analysis considerations for early phase clinical trials in hepatitis B (HBV) cure research: the ACTG A5394 study in persons with both HIV and HBV
por: Kang, Minhee, et al.
Publicado: (2023)

Impact of COVID-19 on people living with HIV: A review
por: Prabhu, Sandeep, et al.
Publicado: (2020)

Awareness, willingness to use, and history of HIV PrEP use among gay, bisexual, and other men who have sex with men in Nigeria
por: Ogunbajo, Adedotun, et al.
Publicado: (2019)

The need for targeted behavioural HIV-related interventions for transgender women in India: A scoping review
por: Lodge, William, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_am98lk0vuiaqe343jgb407srq8