Cargando…

Lack of Evidence for a Role of Islet Autoimmunity in the Aetiology of Canine Diabetes Mellitus

AIMS/HYPOTHESIS: Diabetes mellitus is one of the most common endocrine disorders in dogs and is commonly proposed to be of autoimmune origin. Although the clinical presentation of human type 1 diabetes (T1D) and canine diabetes are similar, the aetiologies may differ. The aim of this study was to in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahlgren, Kerstin M., Fall, Tove, Landegren, Nils, Grimelius, Lars, von Euler, Henrik, Sundberg, Katarina, Lindblad-Toh, Kerstin, Lobell, Anna, Hedhammar, Åke, Andersson, Göran, Hansson-Hamlin, Helene, Lernmark, Åke, Kämpe, Olle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143278/ https://www.ncbi.nlm.nih.gov/pubmed/25153886 http://dx.doi.org/10.1371/journal.pone.0105473

Ejemplares similares

Whole-genome genotyping and resequencing reveal the association of a deletion in the complex interferon alpha gene cluster with hypothyroidism in dogs
por: Bianchi, Matteo, et al.
Publicado: (2020)

Correction: DLA Class II Alleles Are Associated with Risk for Canine Symmetrical Lupoid Onychodystrophy (SLO)
por: Wilbe, Maria, et al.
Publicado: (2010)

DLA Class II Alleles Are Associated with Risk for Canine Symmetrical Lupoid Onychodystropy (SLO)
por: Wilbe, Maria, et al.
Publicado: (2010)

Etiology of Autoimmune Islet Disease: Timing Is Everything
por: Lernmark, Åke
Publicado: (2021)

Comparison of cellular location and expression of Plakophilin‐2 in epidermal cells from nonlesional atopic skin and healthy skin in German shepherd dogs
por: Ardesjö‐Lundgren, Brita, et al.
Publicado: (2017)

A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12
por: Bianchi, Matteo, et al.
Publicado: (2015)

ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease
por: Bremer, Hanna D., et al.
Publicado: (2018)

Multiple Genetic Loci Associated with Pug Dog Thoracolumbar Myelopathy
por: Brander, Gustaf, et al.
Publicado: (2023)

Amylase activity is associated with AMY2B copy numbers in dog: implications for dog domestication, diet and diabetes
por: Arendt, Maja, et al.
Publicado: (2014)

Linked genetic variants on chromosome 10 control ear morphology and body mass among dog breeds
por: Webster, Matthew T., et al.
Publicado: (2015)

Correction: Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis
por: Tengvall, Katarina, et al.
Publicado: (2013)

Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis
por: Tengvall, Katarina, et al.
Publicado: (2013)

Correction: Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis
por: Tengvall, Katarina, et al.
Publicado: (2015)

Multiple regulatory variants located in cell type-specific enhancers within the PKP2 locus form major risk and protective haplotypes for canine atopic dermatitis in German shepherd dogs
por: Tengvall, Katarina, et al.
Publicado: (2016)

A Frameshift Mutation in Golden Retriever Dogs with Progressive Retinal Atrophy Endorses SLC4A3 as a Candidate Gene for Human Retinal Degenerations
por: Downs, Louise M., et al.
Publicado: (2011)

Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency
por: Olsson, Mia, et al.
Publicado: (2015)

Correction: Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency
por: Olsson, Mia, et al.
Publicado: (2015)

High Plasma Levels of Islet Amyloid Polypeptide in Young with New-Onset of Type 1 Diabetes Mellitus
por: Paulsson, Johan F., et al.
Publicado: (2014)

Treatment of diabetic rats with encapsulated islets
por: Sweet, Ian R, et al.
Publicado: (2008)

A Simple Repeat Polymorphism in the MITF-M Promoter Is a Key Regulator of White Spotting in Dogs
por: Baranowska Körberg, Izabella, et al.
Publicado: (2014)

Immunoglobulins in dogs: correspondence and maturation in 15 litters of German shepherd dogs and their dams
por: Vilson, Åsa, et al.
Publicado: (2016)

Swedish Experiences From 60 Years of Screening and Breeding Programs for Hip Dysplasia—Research, Success, and Challenges
por: Hedhammar, Åke
Publicado: (2020)

Two Loci on Chromosome 5 Are Associated with Serum IgE Levels in Labrador Retrievers
por: Owczarek-Lipska, Marta, et al.
Publicado: (2012)

Bayesian model and selection signature analyses reveal risk factors for canine atopic dermatitis
por: Tengvall, Katarina, et al.
Publicado: (2022)

Depleting T Cells in Newly Diagnosed Autoimmune (Type 1) Diabetes—Are We Getting Anywhere?
por: Lernmark, Åke
Publicado: (2013)

Identification of Genomic Regions Associated with Phenotypic Variation between Dog Breeds using Selection Mapping
por: Vaysse, Amaury, et al.
Publicado: (2011)

Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats
por: Medina, Anya, et al.
Publicado: (2017)

What animals can teach us about evolution, the human genome, and human disease
por: Lindblad-Toh, Kerstin
Publicado: (2020)

The ABCC4 gene is associated with pyometra in golden retriever dogs
por: Arendt, Maja, et al.
Publicado: (2021)

SARS-CoV-2 — No Increased Islet Autoimmunity or Type 1 Diabetes in Teens
por: Krischer, Jeffrey P., et al.
Publicado: (2023)

Exploring weight data on over 100,000 Swedish dogs of various breeds
por: Andersson, Linda, et al.
Publicado: (2015)

HLA Genes, Islet Autoantibodies and Residual C-Peptide at the Clinical Onset of Type 1 Diabetes Mellitus and the Risk of Retinopathy 15 Years Later
por: Jensen, Richard A., et al.
Publicado: (2011)

Disentangling factors that shape the gut microbiota in German Shepherd dogs
por: Vilson, Åsa, et al.
Publicado: (2018)

Utilizing the Dog Genome in the Search for Novel Candidate Genes Involved in Glioma Development—Genome Wide Association Mapping followed by Targeted Massive Parallel Sequencing Identifies a Strongly Associated Locus
por: Truvé, Katarina, et al.
Publicado: (2016)

Comment on 'AIRE-deficient patients harbor unique high-affinity disease-ameliorating autoantibodies'
por: Landegren, Nils, et al.
Publicado: (2019)

Impaired Autoimmune T Helper 17 Cell Responses Following DNA Vaccination against Rat Experimental Autoimmune Encephalomyelitis
por: Andersson, Åsa, et al.
Publicado: (2008)

Expression of the coiled coil domain containing protein 116 in the pancreatic islets and endocrine pancreatic tumors
por: Tsolakis, Apostolos V., et al.
Publicado: (2012)

Danish children born with glutamic acid decarboxylase-65 and islet antigen-2 autoantibodies at birth had an increased risk to develop type 1 diabetes
por: Eising, Stefanie, et al.
Publicado: (2011)

Comparative genomics as a tool to understand evolution and disease
por: Alföldi, Jessica, et al.
Publicado: (2013)

Early prediction of autoimmune (type 1) diabetes
por: Regnell, Simon E., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_8lpo0go3h71ep6ka7u0l3lmeub