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Unexpected Phenotype of Mice Lacking Shcbp1, a Protein Induced during T Cell Proliferation

T cell development and activation are highly regulated processes, and their proper execution is important for a competent immune system. Shc SH2-domain binding protein-1 (Shcbp1) is an evolutionarily conserved protein that binds to the adaptor protein ShcA. Studies in Drosophila and in cell lines ha...

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Detalles Bibliográficos
Autores principales: Buckley, Monica W., Arandjelovic, Sanja, Trampont, Paul C., Kim, Taeg S., Braciale, Thomas J., Ravichandran, Kodi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143286/
https://www.ncbi.nlm.nih.gov/pubmed/25153088
http://dx.doi.org/10.1371/journal.pone.0105576

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