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Development of β-Lactoglobulin-Specific Chimeric Human IgEκ Monoclonal Antibodies for In Vitro Safety Assessment of Whey Hydrolysates

BACKGROUND: Cow’s milk-derived whey hydrolysates are nutritional substitutes for allergic infants. Safety or residual allergenicity assessment of these whey hydrolysates is crucial. Currently, rat basophilic leukemia RBL-2H3 cells expressing the human IgE receptor α-chain (huFcεRIα-RBL-2H3), sensiti...

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Detalles Bibliográficos
Autores principales:	Knipping, Karen, Simons, Peter J., Buelens-Sleumer, Laura S., Cox, Linda, den Hartog, Marcel, de Jong, Niels, Teshima, Reiko, Garssen, Johan, Boon, Louis, Knippels, Léon M. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143325/ https://www.ncbi.nlm.nih.gov/pubmed/25153680 http://dx.doi.org/10.1371/journal.pone.0106025

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