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Effects of initial boost with TGF-beta 1 and grade of intervertebral disc degeneration on 3D culture of human annulus fibrosus cells

BACKGROUND: Three-dimensional (3D) culture in porous biomaterials as well as stimulation with growth factors are known to be supportive for intervertebral disc cell differentiation and tissue formation. Unless sophisticated releasing systems are used, however, effective concentrations of growth fact...

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Detalles Bibliográficos
Autores principales:	Hegewald, Aldemar Andres, Cluzel, Jessie, Krüger, Jan Philipp, Endres, Michaela, Kaps, Christian, Thomé, Claudius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143571/ https://www.ncbi.nlm.nih.gov/pubmed/25116605 http://dx.doi.org/10.1186/s13018-014-0073-8

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