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1-Benzyl-1,2,3,4-tetrahydroisoquinoline, an Endogenous Neurotoxic Compound, Disturbs the Behavioral and Biochemical Effects of l-DOPA: In Vivo and Ex Vivo Studies in the Rat

Environmental factors and endogenously produced toxins, such as 1-benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ), are considered to be involved in the pathogenesis of Parkinson’s disease (PD). In this study, we investigated the impact of single and multiple 1BnTIQ (25 and 50 mg/kg i.p.) administrati...

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Detalles Bibliográficos
Autores principales: Wąsik, Agnieszka, Romańska, Irena, Michaluk, Jerzy, Kajta, Małgorzata, Antkiewicz-Michaluk, Lucyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143606/
https://www.ncbi.nlm.nih.gov/pubmed/24842650
http://dx.doi.org/10.1007/s12640-014-9476-x