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False-positive rates in two-point parametric linkage analysis

Two-point linkage analyses of whole genome sequence data are a promising approach to identify rare variants that segregate with complex diseases in large pedigrees because, in theory, the causal variants have been genotyped. We used whole genome sequence data and simulated traits provided by Genetic...

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Detalles Bibliográficos
Autores principales:	Szymczak, Silke, Simpson, Claire L, Cropp, Cheryl D, Bailey-Wilson, Joan E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143621/ https://www.ncbi.nlm.nih.gov/pubmed/25519363 http://dx.doi.org/10.1186/1753-6561-8-S1-S110

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