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Fast genome-wide pedigree quantitative trait loci analysis using MENDEL
The linkage era left a rich legacy of pedigree samples that can be used for modern genome-wide association sequencing (GWAS) or next-generation sequencing (NGS) studies. Family designs are naturally equipped to detect rare variants, control for population stratification, and facilitate the study of...
Autores principales: | Zhou, Hua, Zhou, Jin, Sobel, Eric M, Lange, Kenneth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143629/ https://www.ncbi.nlm.nih.gov/pubmed/25519348 http://dx.doi.org/10.1186/1753-6561-8-S1-S93 |
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