A variance component-based gene burden test

We propose a novel variance component approach for the analysis of next-generation sequencing data. Our method is based on the detection of the proportion of the trait phenotypic variance that can be explained by the introduction of a new variance component that accounts for the local gene-specific...

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Detalles Bibliográficos
Autores principales: Peralta, Juan M, Almeida, Marcio, Kent, Jack W, Blangero, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143638/
https://www.ncbi.nlm.nih.gov/pubmed/25519388
http://dx.doi.org/10.1186/1753-6561-8-S1-S49

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143638/
https://www.ncbi.nlm.nih.gov/pubmed/25519388
http://dx.doi.org/10.1186/1753-6561-8-S1-S49

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